|
KMID : 1038120220550030417
|
|
Clinical Endoscopy
2022 Volume.55 No. 3 p.417 ~ p.425
|
|
|
Feasibility and safety of endoscopic submucosal dissection for lesions in proximity to a colonic diverticulum
|
|
Ikezawa Nobuaki
Toyonaga Takashi
Tanaka Shinwa
Yoshizaki Tetsuya
Takao Toshitatsu
Abe Hirofumi
Sakaguchi Hiroya
Tsuda Kazunori
Urakami Satoshi
Nakai Tatsuya
|
|
|
Abstract
|
|
|
Background/Aims: Endoscopic submucosal dissection (ESD) for diverticulum-associated colorectal lesions is generally contraindicated because of the high risk of perforation. Several studies on patients with such lesions treated with ESD have been reported recently. However, the feasibility and safety of ESD for lesions in proximity to a colonic diverticulum (D-ESD) have not been fully clarified. The aim of this study was to evaluate the feasibility and safety of D-ESD.
Methods: D-ESD was defined as ESD for lesions within approximately 3 mm of a diverticulum. Twenty-six consecutive patients who underwent D-ESD were included. Two strategic approaches were used depending on whether submucosal dissection of the diverticulum-related part was required (strategy B) or not (strategy A). Treatment outcomes and adverse events associated with each strategy were analyzed.
Results: The en bloc resection rate was 96.2%. The R0 and curative resection rates were 76.4% and 70.6% in strategy A and 88.9% and 77.8% in strategy B, respectively. Two cases of intraoperative perforation and one case of delayed perforation occurred. The delayed perforation case required emergency surgery, but the other cases were managed conservatively.
Conclusions: D-ESD may be a feasible treatment option. However, it should be performed in a high-volume center by expert hands because it requires highly skilled endoscopic techniques.
|
|
|
KEYWORD
|
|
|
Colonic diverticulum, Colorectal neoplasms, Endoscopic submucosal dissection, Feasibility, Pocket creation method
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
  
|